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Medicare could save millions if patients with macular degeneration switch to a $50 cancer drug that's just as effective as a $2,000 drug approved for the eye disease. But it was a long haul to get the clinical trial done to prove it.

As President Obama arrived in Alabama to survey damage and meet with officials and devastated survivors, search crews and residents continued to comb the remains of communities pulverized by the nation's deadliest tornado outbreak in nearly four decades. More than 300 were killed across seven states.

The commoners of London stood shoulder to shoulder like flag-waving, wedding-watching sardines with hats for the chance to see Prince William marry Kate Middleton at Westminster Abbey. NPR's Linda Holmes takes in the day's ceremony and spectacle.

Forget Metallica and Megadeth: the lovelorn hero of Jules Massenet's opera 'Werther' romanticizes suicide far more than heavy metal headbangers ever have.

Because of problem with two heaters on one of the shuttle's Auxiliary Power Units, a launch will not happen before Monday.

Wednesday markets the 50th anniversary of the start of the Freedom Rides, when an integrated group of Civil Rights activists rode together by bus through the deep South challenging integration. Historian Raymond Arsenault recounts their journey in Freedom Riders.

Mayors from across the country are assembling in Chicago to find creative ways of cutting costs and raising efficiency. The meeting comes when many mayors are facing budget shortfalls. Host Michel Martin speaks with two of the mayors attending the summit, Philadelphia's Michael Nutter and Los Angeles' Antonio Villaraigosa.

People around the world tuned in Friday morning to watch the Wedding of Prince William and Catherine Middleton, the new duke and duchess of Cambridge. Host Michel Martin discusses how the event influences pop culture with Robin Givhan, special correspondent for style and culture for Newsweek and The Daily Beast.

The White House released President Obama's birth certificate but it still did not silence his critics. Now some are questioning his academic records. Also, a judge's ruling may have ended the NFL lockout, though details of the collective bargaining agreement have yet to be finalized. Host Michel Martin speaks with Tell Me More's Barbershop guys: author Jimi Izrael, civil rights attorney Arsalan Iftikhar, syndicated columnist Ruben Navarrette and Sports Illustrated reporter Pablo Torre.