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President Obama delivered a scathing speech from the Rose Garden late Wednesday, in which he excoriated the Senate for failing to pass gun control legislation that would have required more thorough background checks for buyers of certain firearms.

As the day dawned, officials said an estimated 5 to 15 people were killed and more than 160 were wounded. It was feared those numbers might go higher. The cause of the fire that led to the explosion at a plant near Waco is under investigation.

Also: an animated interview with David Foster Wallace; the self-publishing trend; and a spirited defense of Justin Bieber.

Gun control advocates are regrouping after the Senate's failure to pass new gun regulations on Wednesday. Host Michel Martin talks about the political news of the week with analysts Maria Teresa Kumar, Lenny McAllister and NPR's senior Washington editor, Ron Elving.

A fertilizer plant exploded near Waco, Texas, Wednesday night. Officials report between five and 15 people were killed, and more than 160 wounded.

When volunteer firefighters in the city of West, Texas, about 20 miles north of Waco, arrived to battle a fire at a fertilizer plant, they encountered a disaster in the making. Steve Inskeep and David Greene have more details on the explosion that followed Wednesday night.

Her personality, the times and her background gave Mary Todd Lincoln a place in history and made her one of the more controversial first ladies to occupy…

Time magazine has issued its 100 "most influential people in the world" with two Kentuckians on the list. Actress Jennifer Lawrence—an Academy Award…

Dog owners have similar germs growing on their skin: a signature blend of bacteria from canines' tongues and paws. Scientists couldn't find an analogous signature for cat owners. Perhaps cats are just being selfish.

Investigators have said the key clue is likely to come from photos or video taken by the public, and social media sites are buzzing with theories about possible suspects. But with so many images out there, it's like trying to find the one slightly off-white pingpong ball buried under 10,000 white pingpong balls.